2025 Clinical-Research-Patient-Recruitment- OpenClinica-Recruit
Patient Engagement

Clinical Trial Patient Recruitment

Two Case Studies

Chances are you are all too familiar with the challenges clinical trials face when recruiting patient participants.

  • 85 percent of all clinical trials fail to recruit enough participants.
  • 80 percent are delayed due to low enrollment.
  • 90 percent of clinical trials take twice as long to recruit as their timeline allows.
  • 2 percent of the population participates in clinical trials due to lack of awareness and access.

That’s why the success of BuildClinical – now called OpenClinica Recruit – is so remarkable.

ICYMI, OpenClinica acquired BuildClinical in 2024 to accelerate patient recruitment and enable clinical trials to get better data even faster with our integrated end-to-end technology solution. The company uses advanced data-driven strategies to engage and enroll the ideal clinical trial population needed for a given study. Since its founding in 2020, BuildClinical has enrolled more than 50,000 participants in clinical research studies, while simultaneously accelerating enrollment timelines and reducing participant engagement costs.

OpenClinica Recruit: A Proven Solution to Accelerate Clinical Trial Recruitment

Two case studies demonstrate the success and breadth of OpenClinica Recruit:

1. Obesity in African-American Males in Rural South Carolina Case Study

Problem

The University of South Carolina launched an NIH-funded research study observing health issues in African-American males and geographic factors contributing to obesity. The goal was to recruit obese African-American males between the ages of 25 and 65 living in rural South Carolina that could potentially benefit from a weight loss program. During the first two years of a four year study, the researcher had only recruited three of 30 required participants.

Solution

OpenClinica Recruit’s patient engagement services and tools enabled the researcher to enroll the desired study population by utilizing our algorithm to engage with individuals based on ethnicity, demography, geography and indication. We deployed native advertisements, targeting African-American males with a BMI greater than 25 in specific zip codes across multiple digital platforms and pre-screened interested participants to deliver to the researcher.

Impact

The researcher was able to complete the study well ahead of schedule and accelerate their enrollment 10x-15x the speed using our patient recruitment services. They saw an instant increase in recruitment velocity and were able to better manage potential participants on our tech platform. Further, the researcher was able to reduce their overall study recruitment spend by three times through the use of more targeted advertising strategies.

2. NIH-Sponsored Migraine Case Study

Problem

Albert Einstein College of Medicine launched a remote NIH-funded migraine management research study to help people improve and prevent acute migraine. The goal was to recruit 120 participants living in the United States between the ages of 18 and 65 that struggle with acute migraine.

Solution

OpenClinica Recruit created a customized advertising campaign with study-specific advertisements, a landing page, and a pre-screen questionnaire to engage and enroll acute migraine patients across the United States. Using our machine-learning and algorithmic technologies, we deployed advertisements across digital platforms to engage this population. Our platform enabled the researcher and their team to reach people struggling with migraine and that met all inclusion and exclusion criteria.

Impact

This study was completed ahead of schedule and under budget. Using OpenClinica Recruit, recruitment lasted six months rather than the expected 24 months – 4x faster than expectations. The total campaign was 12x less expensive than what they expected to pay via traditional media outlets. This researcher was able to complete the study and is now starting phase two of the study – and has chosen to once again use OpenClinica Recruit.

To learn more about OpenClinica Recruit, visit here!